Way too soon to tell whether Federal Judge Henry Hudson (a George W. Bush appointee) will gum up the works, but the Washington Post's Ezra Klein says it's another indication that the bill's constitutionality will eventually be determined by the Supreme Court.
Hudson will not have the last word on this. Anthony Kennedy will. The disagreements between the various courts virtually ensure that the Supreme Court will eventually take up the case. But right now, the range of opinions stretch from "the law is fine" to "the individual mandate is not fine, but the rest of the law is." That could create problems for the legislation if the mandate is repealed and Republicans block any attempts at a fix, but it's a far cry from a world in which the Supreme Court strikes down the whole of the health-care law.